Guaifenesin and phenylephrine

Generic name: guaifenesin and phenylephrine [ gwye-FEN-e-sin-and-FEN-il-EFF-rin ]
Brand names: Aldex G, Aquatab D, Deconex, Deconex IR, Donatussin Drops, ... show all 115 brands D-Phen 1000, Duravent PE, Gilphex TR, Liquibid-PD, MucaphEd, Nariz, Prolex D, Sudafed PE Non-Drying Sinus, Supress-PE, Triaminic Chest & Nasal Congestion, Xpect-PE, Sinupan, Deconsal Pediatric, Efasin, Amidal, Chemdal, Quindal, Endal, Liquibid-D, Rescon-GG, SINUvent PE, Entex LA, Entex (obsolete formulation), Crantex, Crantex LA Capsules, Amitex LA, Entex ER, Duraphen II, Crantex ER, Liquibid-D 1200, Phenavent LA, Phenavent D, Sina-12X, Deconsal II, Guaifed Caps, Guaifed PD, Phenavent, Tussbid, Phenavent PED, Nescon-PD, Pendex, Prolex PD, Aldex, Nasex, Crantex LA Tablets, Duratuss, Duratuss GP, Lusonex, Sitrex, Guaiphen-PD, Wellbid-D, Wellbid-D 1200, Despec, Xedec, Nasex-G, Gentex LA, Guaiphen-D 600, Guaiphen-D 1200, Simuc, Zotex GPX, Duomax, Guaifen PE, Norel EX, Nexphen PD, Respa-PE, Reluri, Duraphen 1000, Dynex LA, Sudex, Extendryl G, Maxiphen, Ambi 40/1000, MontePhen, Xedec II, Simuc-GP, Triaminic Chest and Nasal Congestion, Duratuss PE, Sitrex PD, Refenesen PE, Mydex, Medent-PE, Genexa LA, Nazarin, J-Max, Mucus Relief Sinus, Robitussin Head and Chest Congestion, Visonex, Zyrphen, PE-Guai, Guiadex PD, D-Tab, ExeTuss, ExeTuss-GP, Mucinex Children's Cold, Quintex, Guiatex PE, Fenesin PE IR, Medent-PEI, Liquibid PD-R, Liquibid D-R, Zoden Drops, Entex LQ, Tussi-Pres PE, Lusair, Reese Onetab Congestion and Cough, ED Bron GP, Relcof IR, Giltuss Sinus and Congestion, Mucinex Children's Stuffy Nose and Chest Congestion, Maxi-Tuss PE Jr
Dosage forms: oral drops (20 mg-1.5 mg/mL); oral liquid (200 mg-7.5 mg/5 mL; 50 mg-2.5 mg/5 mL; 50 mg-2.5 mg/mL); oral tablet (200 mg-5 mg; 380 mg-10 mg; 385 mg-10 mg; 388 mg-10 mg; 395 mg-10 mg; 400 mg-10 mg); oral tablet, extended release (1000 mg-30 mg; 1100 mg-30 mg; 1200 mg-25 mg; 1200 mg-30 mg; 315 mg-20 mg; 600 mg-20 mg; 835 mg-25 mg; 835 mg-30 mg)
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com on Jan 17, 2022. Written by Cerner Multum.

What is guaifenesin and phenylephrine?

There are many brands and forms of guaifenesin and phenylephrine available and not all brands are listed on this leaflet.

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Guaifenesin and phenylephrine is a combination medicine used to treat stuffy nose