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Guaifenesin Tablets
  • Professionals
  • FDA PI

Guaifenesin Tablets

Dosage form: tablet
Drug class:Expectorants

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Guaifenesin Tablets Description

Guaifenesin (glyceryl guaiacolate) has the chemical name 3-(2-methoxyphenoxy)-1,2-propanediol. Its molecular formula is C10H14O4 with a molecular weight of 198.21. It is a white or slightly gray crystalline substance with a slightly bitter aromatic taste. One gram dissolves in 20 mL water at 25°C; it is freely soluble in ethanol. Guaifenesin is readily absorbed from the GI tract and is rapidly metabolized and excreted in the urine. Guaifenesin has a plasma half-life of one hour. The major urinary metabolite is β-(2-methoxyphenoxy) lactic acid.

Guaifenesin is an expectorant available for oral administration as:

Tablets — each containing 200 mg guaifenesin, USP.

Other ingredients: crospovidone, D&C red #30 aluminum lake, magnesium stearate, microcrystalline cellulose, polysaccharides, pregelatinized starch, silicon dioxide, sodium starch glycolate, and stearic acid.

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