Guanidine

Generic name: guanidine [ GWAN-ih-deen ]
Brand name: Guanidine HCl
Dosage form: oral tablet (125 mg)
Drug class:Cholinergic muscle stimulants

Medically reviewed by Drugs.com on Jan 14, 2022. Written by Cerner Multum.

What is guanidine?

Guanidine is used to treat muscle weakness caused by Eaton-Lambert syndrome. Guanidine will not treat myasthenia gravis.

Guanidine may also be used for purposes not listed in this medication guide.

Warnings

Guanidine can increase your risk of bleeding or infection. Call your doctor if you have unusual bruising or bleeding, or new signs of infection (fever, chills, tiredness, mouth sores).

Before taking this medicine

You should not use guanidine if you are allergic to it.

Tell your doctor if you have ever had a weak immune system (caused by disease or by using certain medicine).

It is not known whether guanidine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breast-feed while using this medicine.

Guanidine is not approved for use by anyone younger than 18 years old.

How should I take guanidine?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Guanidine doses are based on weight. Your dose needs may change if you gain or lose weight.

Guanidine can increase your risk of bleeding or infection. You will need frequent medical tests.

Your kidney function may also need to be checked.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include diarrhea, vomiting, tremors, and severe muscle spasms or twitching.

What should I avoid while taking guanidine?

Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.

Guanidine side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Guanidine may cause serious side effects. Call your doctor at once if you have:

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