HT-Tuss DM Elixir

Generic name:dextromethorphan hydrobromide and guaifenesin
Dosage form: elixir
Drug class:Upper respiratory combinations

Medically reviewed by Drugs.com. Last updated on Sep 21, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

HT-Tuss DM Elixir Description

Each 5 mL (one teaspoonful) of HT-Tuss DM Elixir contains:

Dextromethorphan hydrobromide . . . 20 mg

Guaifenesin . . . . 200 mg

Alcohol . . . . . . . . . . . 5%

Also contains: Citric acid, FD&C blue #1, FD&C red #3, FD&C red #40, high fructose corn syrup, natural & artificial grape flavor, propylene glycol, purified water, saccharin sodium, sodium benzoate. Sodium citrate may be used to adjust pH.

Dextromethorphan hydrobromide, a synthetic monopioid antitussive, is a salt of the methyl ether of the dextrorotatory isomer of levorphanol, an opioid analgesic. The chemical name is 3- methoxy-17-methyl-9α, 13α, 14α-morphinan hydrobromide monohydrate. It has the following structural formula:

Guaifenesin is an expectorant. The chemical name is (±)-3-(o- Methoxyphenoxy)-1,2- propanediol. It has the following structural formula:

HT-Tuss DM Elixir - Clinical Pharmacology

HT-Tuss DM Elixir combines the cough suppressant dextromethorphan hydrobromide and the expectorant guaifenesin.

Dextromethorphan hydrobromide is a non-opioid antitussive agent. Dextromethorphan temporarily controls and suppresses the cough reflex by a direct action on the cough center. It has no significant analgesic or sedative properties, does not depress respiration or predispose to addiction with usual doses. In therapeutic dosage, dext...