Hydroxyethyl Starch in Sodium Chloride
Dosage form: injection, solution
Drug class:Plasma expanders
Medically reviewed by Drugs.com. Last updated on Jul 1, 2020.
On This Page
- Boxed Warning
- Indications and Usage
- Dosage and Administration
- Dosage Forms and Strengths
- Contraindications
- Warnings and Precautions
- Adverse Reactions/Side Effects
- Drug Interactions
- Use In Specific Populations
- Overdosage
- Description
- Clinical Pharmacology
- Nonclinical Toxicology
- Clinical Studies
- References
- How Supplied/Storage and Handling
- Patient Counseling Information
- In critically ill adult patients, including patients with sepsis, use of hydroxyethyl starch (HES) products, including6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride injection, increases risk of
- Mortality
- Renal replacement therapy
- Do not use HES products, including6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride injection, in critically ill adult patients, including patients with sepsis.
Indications and Usage for Hydroxyethyl Starch in Sodium Chloride
6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride injection is indicated for the treatment and prophylaxis of hypovolemia in adults and children. It is not a substitute for red blood cells or coagulation factors in plasma.
Hydroxyethyl Starch in Sodium Chloride Dosage and Administration
6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride injection is administered by intravenous infusion only. The daily dose and rate of infusion depend on the patient's blood loss, on the maintenance or restoration of hemodynamics and on the hemodilution (dilution effect). 6% hydroxyethyl starch 130/0.4 in 0.9% sodium chloride injectioncan be administered repetitively over several days. [see Warnings and Precautions (5)...
