HyoMax-DT

Generic name:hyoscyamine sulfate
Dosage form: tablet
Drug class:Anticholinergics / antispasmodics

Medically reviewed by Drugs.com. Last updated on Aug 23, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

DESCRIPTION:

Each purple and white, biphasic, capsule shaped tablet for oral administration is specially formulated to release 0.125 mg of hyoscyamine sulfate immediately and 0.250 mg of hyoscyamine sulfate over the remaining 8 to 12 hours of the dosing period.

I-Hyoscyamine sulfate is one of the principal anticholinergic/antispasmodic components of belladonna alkaloids.

Hyoscyamine sulfate is Benzeneacetic acid, α-(hydroxymethyl)-, 8 methyl-8-azabicyclo[3.2.1]oct-3-yl ester, [3(S)-endo]-, sulfate (2:1), dihydrate.

hyoscyamine sulfate

Inactive ingredients include calsium phosphate, D&C Red #30, FD&C Blue #1, lactose monohydrate, magnesium stearate, methylcullulose, povidone, silicified microcrystalline cellulose, sodium starch glycolate.

CLINICAL PHARMACOLOGY:

HyoMax®-DT inhibits specifically the actions of acetylcholine on structures innervated by postganglionic cholinergic nerves and on smooth muscles that respond to acetylcholine but lack cholinergic innervation. These peripheral cholinergic receptors are present in the autonomic effector cells of the smooth muscle, the cardiac muscle, the sinoatrial node, the atrioventricular node, and the exocrine glands. At therapeutic doses, it is completely devoid of any action on autonomic ganglia. HyoMax®-DT inhibits gastrointestinal propulsive motility and decreases gastric acid secretion. HyoMax®-DT also controls excessive pharyngeal, tracheal, and bronchial secretions.

Hyoscyamine sulfate is absorbed totally and completely by oral administration. Once absorbed, it disappears rapidly from the blood and is distributed through the entire body: ...