Hyzaar

Generic name:hydrochlorothiazide and losartan [ HYE-droe-KLOR-oh-THYE-a-zide-and-loe-SAR-tan ]
Drug class:Angiotensin II inhibitors with thiazides

Medically reviewed by Philip Thornton, DipPharm. Last updated on Feb 28, 2021.

What is Hyzaar?

Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.

Losartan is an angiotensin II receptor antagonist (sometimes called an ARB blocker). Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Hyzaar is used to treat high blood pressure (hypertension).

Hyzaar is also used to lower the risk of stroke in certain people with heart disease.

Warnings

Do not use Hyzaar if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant.

You should not use this medicine if you are unable to urinate.

If you have diabetes, do not use Hyzaar together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Hyzaar with aliskiren if you have kidney disease.

In rare cases, Hyzaar can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

Before taking this medicine

You should not use Hyzaar if you are allergic to hydrochlorothiazide or ...