Generic name:azathioprine (intravenous route) [ ay-za-THYE-oh-preen-SOE-dee-um ]
Drug classes:Antirheumatics, Other immunosuppressants
Medically reviewed by Drugs.com. Last updated on Apr 22, 2022.
Chronic immunosuppression with azathioprine, a purine antimetabolite, increases risk of malignancy in humans. Reports of malignancy include post-transplant lymphoma and hepatosplenic T-cell lymphoma (HSTCL) in patients with inflammatory bowel disease. Physicians using this drug should be very familiar with this risk as well as with the mutagenic potential to both men and women and with possible hematologic toxicities. Physicians should inform patients of the risk of malignancy with azathioprine .
Commonly used brand name(s)
In the U.S.
- Imuran
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antirheumatic, Cytotoxic
Pharmacologic Class: Azathioprine
Uses for Imuran
Azathioprine injection is used to prevent rejection of a transplanted kidney. It belongs to the group of medicines known as immunosuppressive agents. Azathioprine will lower the body's natural immunity in patients who receive transplants to prevent rejection of the new kidney. It is also used to relieve joint pain and swelling for patients with active rheumatoid arthritis.
This medicine is to be given only by or under the direct supervision of your doctor.
Before using Imuran
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ..
