Inclisiran (Subcutaneous)
Medically reviewed by Drugs.com. Last updated on Mar 2, 2022.
Commonly used brand name(s)
In the U.S.
- Leqvio
Available Dosage Forms:
- Solution
Therapeutic Class: Antihyperlipidemic
Uses for inclisiran
Inclisiran injection is used together with a proper diet, alone or together with other medicines (eg, statins), to treat heterozygous familial hypercholesterolemia (HeFH) or clinical atherosclerotic cardiovascular disease (ASCVD) in patients who need additional lowering of their LDL cholesterol.
Inclisiran is to be given only by or under the direct supervision of your doctor.
Before using inclisiran
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For inclisiran, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to inclisiran or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of inclisiran injection in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of inclisiran injection in the elderly. However, elderly patients are more sensitive to the effects of inclisiran than younger adults.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper use of inclisiran
A nurse or other trained health professional will give you inclisiran. It is given as a shot under your skin, usually in the stomach, thighs, or upper arms.
In addition to inclisiran, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. Carefully follow your doctor's order about any special diet.
Missed dose
Call your doctor or pharmacist for instructions.