Incobotulinumtoxina (Intramuscular)
Medically reviewed by Drugs.com. Last updated on Dec 17, 2021.
Distant Spread of Toxin EffectThe effects of incobotulinumtoxinA and all botulinum toxin products may spread from the area of injection to produce symptoms consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably greatest in children treated for spasticity, but symptoms can also occur in adults, particularly in those patients who have underlying conditions that would predispose them to these symptoms .
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Musculoskeletal Agent
Pharmacologic Class: Botulinum Toxin Type A
Uses for incobotulinumtoxina
IncobotulinumtoxinA is used to treat the abnormal head position and neck pain that result from cervical dystonia (severe muscle spasms of the neck). It is also used to treat upper limb spasticity (muscle spasms in the upper arms). Incobotulinumtoxina is also used to treat blepharospasm, a condition wherein the eyelid will not stay open because of a muscle spasm. It is also used to treat long-lasting sialorrhea (excessive drooling). IncobotulinumtoxinA is also used cosmetically to improve the appearance of deep facial lines or wrinkles between the eyebrows (glabellar lines).
IncobotulinumtoxinA is a botulinum toxin A product. It works on the nervous system to relax the muscles.
Incobotulinumtoxina is to be given only by or under the direct supervision of your doctor.
Before using incobotulinumtoxina
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For incobotulinumtoxina, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to incobotulinumtoxina or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of incobotulinumtoxinA in children with lower limb spasticity, cervical dystonia, blepharospasm, or glabellar frown lines. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of incobotulinumtoxinA in children 2 to 17 years of age with sialorrhea or upper limb spasms, excluding spasms caused by cerebral palsy. Safety and efficacy have not been established in children younger than 2 years of age.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of incobotulinumtoxinA in the elderly. However, elderly patients are more sensitive to the effects of incobotulinumtoxina than younger adults and are more likely to have side effects (eg, difficulty with swallowing, lack or loss of strength, or dizziness), which may require caution in patients receivi..
