Medically reviewed by Drugs.com. Last updated on Oct 29, 2021.
NSAIDs cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Indomethacin is contraindicated in the setting of CABG surgery. NSAIDs can also cause an increased risk of serious gastrointestinal (GI) adverse events, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at a greater risk for serious GI events .
Commonly used brand name(s)
In the U.S.
- Indocin
In Canada
- Indocid
- Novo-Methacin Suppositories
- Ratio-Indomethacin
- Rhodacine
Available Dosage Forms:
- Suppository
Therapeutic Class: Analgesic
Pharmacologic Class: NSAID
Chemical Class: Acetic Acid (class)
Uses for indomethacin
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used to help relieve symptoms of moderate to severe arthritis (eg, osteoarthritis and rheumatoid arthritis) or gout, such as inflammation, swelling, stiffness, and joint pain. However, indomethacin does not cure arthritis and will help you only as long as you continue to use it.
Indomethacin is also used to treat moderate to severe ankylosing spondylitis, which is a type of arthritis that affects the joints in the spine. Indomethacin may also be used to treat painful shoulder caused by bursitis or tendinitis.
Indomethacin is available only with your doctor's prescription.
Before using indomethacin
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For indomethacin, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to indomethacin or any other medicines. Also tell your health car..