Inebilizumab
Generic name: inebilizumab [ in-EB-i-LIZ-ue-mab ]
Brand name: Uplizna
Dosage form: intravenous solution (100 mg/10 mL)
Drug class:Selective immunosuppressants
What is inebilizumab?
Inebilizumab is used in adults with a condition called neuromyelitis optica (NOO-roe-mye-LYE-tis OP-ti-ka) spectrum disorder (NMOSD), and who are positive for a certain antibody.
NMOSD, also called Devic's disease, is a central nervous system disorder that occurs when your immune system attacks cells in your eyes, spinal cord, or brain. NMOSD may cause vision loss, weakness or paralysis in your arms or legs, numbness or pain, uncontrollable vomiting or hiccups, or loss of bowel or bladder control.
Inebilizumab can help lower your risk of having these symptoms or developing a permanent disability.
Inebilizumab may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not be treated with inebilizumab if you have:
active hepatitis B;
active or untreated tuberculosis; or
a history of life-threatening reaction to an inebilizumab injection.
Tell your doctor if you think you have an infection, or if you have ever had:
hepatitis B (or if you are a carrier);
tuberculosis; or
if you have recently received or are scheduled to receive a vaccine.
Make sure you are current on all vaccines at least 4 weeks before you start treatment with inebilizumab.
Inebilizumab may harm an unborn baby. Use effective birth control to prevent pregnancy while using inebilizumab and for at least 6 months after your last dose.
If you use inebilizumab while you are pregnant, make sure any doctor caring for your new baby knows that you used this medicine during pregnancy. Being exposed to inebilizumab in the womb could affect your baby's vaccination schedule during the first few months of life.
It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.
How is inebilizumab given?
Inebilizumab is given as an infusion into a vein. A healthcare provider will give you this injection.
Inebilizumab must be given slowly, and the infusion can take at least 90 minutes to complete.
Before each infusion, your doctor will perform tes...
