Infigratinib
Generic name: infigratinib [ IN-fig-RA-ti-nib ]
Brand name: Truseltiq
Dosage form: oral capsule (100 mg daily-dose; 125 mg daily-dose; 50 mg daily-dose; 75 mg daily-dose)
Drug class:Multikinase inhibitors
What is infigratinib?
Infigratinib is used to treat bile duct cancer that has an abnormal "FGFR2" gene and has spread to other parts of the body (metastatic) after other treatment, and cannot be removed with surgery. Your doctor will make sure you have the correct tumor type to be treated with infigratinib.
Infigratinib may also be used for purposes not listed in this medication guide.
Warnings
Follow all directions on the label and package. Use exactly as directed.
Before taking this medicine
Tell your doctor if you have ever had:
problems with your eyes or vision;
liver disease; or
kidney disease.
You may need to have a negative pregnancy test before starting this treatment.
Infigratinib can harm an unborn baby if the mother or the father is using infigratinib. Use birth control while using this medicine and for at least 1 month after your last dose.
Do not breastfeed while using this medicine, and for at least 1 month after your last dose.
How should I take infigratinib?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Infigratinib is given in a 28-day treatment cycle and you will take the medicine only on certain days of this cycle.
Take on an empty stomach, at least 1 hour before or 2 hours after a meal.
Take the medicine at the same time each day.
Swallow the capsule whole and do not crush, chew, break, or open it. Take with a full glass of water.
If you vomit shortly after taking infigratinib, do not take another dose. Take your next dose as scheduled.
You may need frequent vision exams. You may need to use artificial tears or lubricating eye gels if you have dry eyes.
Store tablets in the blister pack at room temperature away from moisture and heat.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if you are more than 4 hours late for the dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking infigratinib?
Grapefruit may interact with infigratinib and cause side effects. Avoid consuming grapefruit products.
Avoid taking an antacid withi...
