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Iprivask
  • Treatments
  • Deep Vein Thrombosis
  • Prophylaxis

Iprivask

Generic name:desirudinDES-i-ROO-din ]
Drug class:Thrombin inhibitors

Medically reviewed by Drugs.com on Mar 15, 2022. Written by Cerner Multum.

What is Iprivask?

Iprivask is an anticoagulant (thrombin inhibitor) that helps prevent the formation of blood clots.

Iprivask is used to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can occur after certain types of surgery. This medicine is for use after hip replacement surgery.

Iprivask may also be used for purposes not listed in this medication guide.

Warnings

You should not use Iprivask if you have active or uncontrolled bleeding, or an irreversible blood clotting disorder.

Iprivask can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural), especially if you are also using other drugs that can affect blood clotting, including blood thinners or NSAIDs (ibuprofen, Advil, Aleve, and others). This type of blood clot can lead to long-term or permanent paralysis.

Get emergency medical help if you have symptoms of a spinal cord blood clot such as back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Before taking this medicine

You should not use this medicine if you are allergic to Iprivask, bivalirudin, or lepirudin, or if you have:

  • active or uncontrolled bleeding; or

  • an irreversible blood clotting disorder.

Iprivask can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term or permanent paralysis, and may be more likely to occur if:

  • you have a spinal cord injury;

  • you have a spinal catheter in place;

  • you have a history of spinal surgery or repeated spinal taps;

  • you are taking an NSAID (nonsteroidal anti-inflammatory drug)--ibuprofen (Advil, Motrin), naproxen (Aleve), diclofenac, indomethacin, meloxicam, and others; or

  • you are using a blood thinne...