Irinotecan

Generic name: irinotecan [ EYE-ri-noe-TEE-kan ]
Brand name: Camptosar
Dosage form: intravenous solution (20 mg/mL)
Drug class:Miscellaneous antineoplastics

Medically reviewed by Drugs.com on Apr 13, 2021. Written by Cerner Multum.

What is irinotecan?

Irinotecan is used to treat cancers of the colon and rectum. It is usually given with other cancer medicines.

Irinotecan may also be used for purposes not listed in this medication guide.

Warnings

Irinotecan can cause severe diarrhea, which can be life-threatening. Call your doctor whenever you have diarrhea during your treatment with irinotecan.

Before taking this medicine

You should not use irinotecan if you are allergic to it.

Tell your doctor if you have ever had:

• liver or kidney disease;

• lung disease;

• an intestinal disorder or obstruction;

• Gilbert's syndrome;

• fructose intolerance (irinotecan contains sorbitol);

• radiation treatment to your abdomen or pelvic area; or

• if you take a diuretic or "water pill."

Irinotecan can harm an unborn baby if the mother or the father is using irinotecan.

• If you are a woman, you may need to have a negative pregnancy test. Use effective birth control to prevent pregnancy while you are using this medicine and for at least 6 months after your last dose.

• If you are a man, use effective birth control if your sex partner is able to get pregnant. Keep using birth control for at least 3 months after your last dose.

• Tell your doctor right away if a pregnan...