Isatuximab
Generic name: isatuximab [ EYE-sa-TUX-i-mab ]
Brand name: Sarclisa
Dosage form: intravenous solution (irfc 20 mg/mL)
Drug class:CD38 monoclonal antibodies
What is isatuximab?
Isatuximab is used treat multiple myeloma in adults. Isatuximab is usually given in combination with another cancer medicine (carfilzomib or pomalidomide) and a steroid (dexamethasone).
Isatuximab is given after other cancer treatments did not work or have stopped working.
Isatuximab may also be used for purposes not listed in this medication guide.
Warnings
Before using isatuximab tell your doctor about all your medical conditions or allergies, all medicines you use, and if you are pregnant or breastfeeding.
Before taking this medicine
You should not be treated with isatuximab if you are allergic to it.
You may need to have a negative pregnancy test before starting this treatment.
Isatuximab may harm an unborn baby. Use effective birth control to prevent pregnancy while you are using isatuximab and for at least 5 months after your last dose.
If you use isatuximab while you are pregnant, make sure any doctor caring for your new baby knows that you used this medicine during pregnancy. Being exposed to isatuximab in the womb could affect your baby's vaccination schedule during the first few months of life.
You should not use isatuximab together with pomalidomide if you are pregnant or planning to become pregnant. Pomalidomide can cause severe, life-threatening birth defects with just one dose.
Both men and women using pomalidomide should use effective birth control to prevent pregnancy. Tell your doctor right away if a pregnancy occurs while either the mother or the father is using isatuximab and pomalidomide.
You should not breastfeed while using isatuximab.
Using isatuximab may increase your risk of developing other cancers. Ask your doctor about this risk.
How is isatuximab given?
Isatuximab is given as an infusion into a vein. A healthcare provider will give you this injection.
You will be watched closely for at least 30 minutes after your first 2 infusions to make sure you do not have an allergic reaction.
Isatuximab is given in a 28-day treatment cycle. You may need to use the medicine only during certain days of each cycle. Your doctor will determine how long to treat you with this medicine.
You may be given other medications to help prevent serious side effects or an allergic reaction. Keep using these medicines for as long as your doctor has prescribed.
Read all medication guides you receive for the other medicines used in combination with isatuximab.
Isatuximab can lower your...
