Isoflurane Veterinary
Generic name: isoflurane inhalant
Dosage form: FOR ANIMAL USE ONLY
CAUTION: Federal law restricts this drug to use by or on the order of a licensed veterinarian.
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Isoflurane Veterinary Description
Isoflurane (Isoflurane, USP) is a nonflammable, nonexplosive general inhalation anesthetic agent. Its chemical name is 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether, and its structural formula is:
Each mL contains 99.9% Isoflurane.
Some physical constants are:
| Molecular weight | 184.5 | |
| Boiling point at 760 mmHg | 48.5°C (uncorr.) | |
| Refractive i n d e x n20/D | 1.2990-1.3005 | |
| Specific gravity 25°/25°C | 1.496 | |
| Vapor pressure in mmHg** | 20°C 238 | |
| 25°C 295 | ||
| 30°C 367 | ||
| 35°C 450 |
log10Pvap = A + B/T
where: A = 8.056
B = -1664.58
T = °C + 273.16 (Kelvin)
Partition coefficients at 37°C
| Water/gas | 0.61 |
| Blood/gas | 1.43 |
| Oil/gas | 90.8 |
| Partition coefficients at 25°C - rubber and plastic | |
| Conductive rubber/gas | 62.0 |
| Butyl rubber/gas | 75.0 |
| Polyvinyl chloride/gas | 110.0 |
| Polyethylene/gas | ~2.0 |
| Polyurethane/gas | ~1.4 |
| Polyolefin/gas | ~1.1 |
| Butyl acetate/gas |

