#
Isolyte S
  • Professionals
  • FDA PI

Isolyte S

Generic name:sodium chloride, sodium gluconate, sodium acetate, potassium chloride, and magnesium chloride
Dosage form: injection, solution
Drug class:Intravenous nutritional products

Medically reviewed by Drugs.com. Last updated on Apr 21, 2022.

Isolyte S Description

Each 100 mL of Isolyte® S (Multi-Electrolyte Injection) contains:
Sodium Chloride USP 0.53 g; Sodium Gluconate USP 0.5 g
Sodium Acetate Trihydrate USP 0.37 g; Potassium Chloride USP 0.037 g
Magnesium Chloride Hexahydrate USP 0.03 g
Water for Injection USP qs

pH adjusted with Glacial Acetic Acid USP
pH: 6.7 (6.3–7.3)
Calculated Osmolarity: 295 mOsmol/liter

Concentration of Electrolytes (mEq/liter): Sodium 140; Potassium 5
Magnesium 3; Chloride 98; Acetate (CH3COO) 27
Gluconate (HOCH2(CHOH)4COO) 23

Isolyte® S is sterile, nonpyrogenic, and contains no bacteriostatic or antimicrobial agents.

The formulas of the active ingredients are:

IngredientsMolecular
Formula
Molecular
Weight
Sodium Chloride USP NaCl 58.44
Sodium Acetate Trihydrate USP CH3COONa•3H2O 136.08
Potassium Chloride USP KCl 74.55
Magnesium Chloride Hexahydrate USP MgCl2•6H2O 203.30
Sodium Gluconate USP

218.14

Not made with natural rubber latex, PVC or DEHP.

The plastic container is made from a multilayered film specifically developed for parenteral drugs. It contains no plasticizers and exhibits virtually no leachables. The solution contact layer is a rubberized copolymer of ethylen