Isoplate
Generic name: sodium chloride, sodium gluconate, sodium acetate, potassium chloride, magnesium chloride, sodium phosphate, dibasic and potassium phosphate, monobasic
Dosage form: intravenous solution
Drug class:Intravenous nutritional products
Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.
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Indications and Usage for Isoplate
Isoplate SOLUTION - Platelet Additive Solution [PAS-F] is an isotonic solution to replace a portion of the plasma to store Platelets Pheresis Platelet Additive Solution (PAS) Added Leukocytes Reduced products collected using a hyperconcentrated collection on Terumo BCT's Trima Accel system [See Dosage and Administration (2).]
Platelets Pheresis PAS Added Leukocytes Reduced products are stored in a mix of 65% Isoplate SOLUTION and 35% plasma. Platelets in the solution can be stored at a concentration range of 0.7 to 2.1 × 106/µL for up to 5 days at 20-24 °C with continuous agitation in the Terumo BCT ELP bag [citrated polyvinyl chloride (PVC)] [See Clinical Studies (14).]
Isoplate Dosage and Administration
General Dosing Information
Isoplate SOLUTION is added to hyperconcentrated platelets after the apheresis procedure is complete. It is not intended for direct intravenous infusion.
Isoplate SOLUTION may only be used with the Trima Accel system for automated blood collection. For instructions on the use of the solution with the Trima Accel system, see the Trima Accel system operator's manual.
Administration
- Ensure solution is the Isoplate SOLUTION and is within the expiration date.
- Inspect the bag. Do not use if the container is damaged, leaking or if there is any visible sign of deterioration.
- Use only if solution is clear and free of particulate matter.
- Protect from sharp objects.
Directions for Connecting the Isoplate SOLUTION Bag to the Trima Accel System
At the prompt to connect the platelet additive solution to the Trima Accel system tubing set:
- Remove the overwrap by pulling down at notch, and remove the Isoplate SOLUTION bag.
- Before use, perform the following checks
