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Jay-Phyl Syrup
  • Professionals
  • FDA PI

Jay-Phyl Syrup

Generic name:dyphylline and guaifenesin
Dosage form: oral syrup
Drug class:Antiasthmatic combinations

Medically reviewed by Drugs.com. Last updated on Nov 22, 2021.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Jay-Phyl Syrup

Bronchodilator/Expectorant
Rx Only

DESCRIPTION:
Jay-Phyl Syrup is a bronchodilator/expectorant combination supplied as a Orange, Vanilla flavored,
alcohol free and gluten free liquid for oral administration.

Each teaspoonful (5 mL) contains:
Dyphylline..... 100 mg
Guaifenesin..... 50 mg

Inactive ingredients: Glycerin, Propylene Glycol, Sorbitol, Citric Acid, Sodium Citrate, Sodium
Saccharin, Vanilla Flavor, FD and C Yellow No. 6, Purified Water.

Dyphylline is 7-(2,3-dihydroxypropyl)-theophylline, a white, extremely bitter, amorphous powder that is fully
soluble in water and soluble in alcohol to the extent of 2 g/100 mL. Dyphylline forms a neutral solution that
is stable in gastrointestinal fluids over a wide range of pH. It has the following chemical structure:



Guaifenesin is an expectorant which occurs as a white to slightly gray, crystalline powder, having a bitter
taste. It may have a slight characteristic odor. It is soluble in water, alcohol, chloroform, glycerin, and
propylene glycol. The chemical name is 1,2-Propanediol, 3-(2-methoxyphenoxy)-, (±)-. It has the following
chemical structure:

Jay-Phyl Syrup - Clinical Pharmacology

Dyphylline is a xanthine derivative with pha