Kaletra

Generic name:lopinavir and ritonavir [ loe-PIN-a-vir-and-ri-TOE-na-veer ]
Drug class:Protease inhibitors

Medically reviewed by Philip Thornton, DipPharm. Last updated on May 4, 2021.

What is Kaletra?

Kaletra contains a combination of lopinavir and ritonavir. Lopinavir and ritonavir are antiviral medications that prevent the human immunodeficiency virus (HIV) from multiplying in your body.

Kaletra is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS).

Kaletra is not a cure for HIV or AIDS.

Warnings

Kaletra can cause a serious heart problem, especially if you use certain other medicines at the same time. Tell your doctor about all your current medicines and any medicine you start or stop using.

Call your doctor at once if you have a headache with chest pain, fast or pounding heartbeats, and severe dizziness.

Before taking this medicine

You should not use Kaletra if you have ever had a severe allergic reaction to lopinavir or ritonavir.

Some medicines can cause unwanted or dangerous effects when used with Kaletra. Your doctor may need to change your treatment plan if you use any of the following drugs:

• alfuzosin;

• apalutamide;

• cisapride;

• colchicine;

• dronedarone;

• elbasvir/grazoprevir;

• lomitapide;

• lurasidone, pimozide;

• ranolazine;

• rifampin;

• lovastatin, simvastatin;

• triazolam, or oral midazolam;

• sildenafil (Revatio for pulmonary arterial hypertension);

• St. John's wort; or

• an ergot medicine (ergotamine, dihydroergotamine, methylergonovine).

To make sure Kaletra is safe for you, tell your doctor if you ha...