ACD A

Generic name: citric acid monohydrate, dextrose monohydrate, and trisodium citrate dihydrate
Dosage form: injection, solution

Indications and Usage for ACD A

ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is an anticoagulant for blood collection for use only with apheresis devices. [See Dosage and Administration (2).]

ACD A Dosage and Administration

General Dosing Information

ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A is added to tubing sets during apheresis procedures. The solution is connected to the tubing set in an apheresis collection. The recommended dose is determined by the apheresis device and metered into the tubing set by the apheresis device. It is not intended for direct intravenous infusion.

For instructions on the use of the solution with the apheresis device and tubing set, see the device operator's manual.

Administration

• Ensure solution is the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A and is within the expiration date.
• Inspect the bag. Do not use if the container is damaged, leaking or if there is any visible sign of deterioration.
• Use only if solution is clear and free of particulate matter.
• Protect from sharp objects.

Directions for Connecting the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A bag to the apheresis device.

At the prompt to connect anticoagulant to the apheresis device tubing set:

1. Remove the overwrap by pulling down at notch, and remove the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A bag.
2. Before use, perform the following checks [See Warnings and Precautions (5).]:
   • Check for leaks by gently squeezing the bag. If leaks are found, discard the bag.
   • Ensure that the solution is the ANTICOAGULANT CITRATE DEXTROSE SOLUTION USP (ACD) SOLUTION A and is within the expiration date.
   • Inspect the solution in adequate light. Bags showing cloudiness, haze, or particulate matter should not be used.
3. Remove the protective cap from the port on the bag.
4. Connect the bag to the apheresis device tubing set using aseptic technique and hang the solution.
5. Break the frangible connector. When you break frangible connectors, bend them in both directions to ensure that you break them completely. Failure to do so may result in restricted flow.
6. Proceed according to the aphe..