Kazano

Generic name:alogliptin and metformin [ AL-oh-GLIP-tin-and-met-FOR-min ]
Drug class:Antidiabetic combinations

Medically reviewed by Philip Thornton, DipPharm. Last updated on Apr 25, 2022.

What is Kazano?

Kazano contains a combination of alogliptin and metformin. Alogliptin and metformin are oral diabetes medicines that help control blood sugar levels.

Metformin works by decreasing glucose (sugar) production in the liver and decreasing absorption of glucose by the intestines. Alogliptin works by regulating the levels of insulin your body produces after eating.

Kazano is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Kazano is not for treating type 1 diabetes.

Warnings

You should not use Kazano if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.

Alogliptin can cause pancreatitis. Stop using Kazano and call your doctor at once if you have severe pain in your upper stomach spreading to your back, nausea and vomiting, and loss of appetite.

Before taking this medicine

You should not use Kazano if you are allergic to alogliptin or metformin, or if you have severe kidney disease or diabetic ketoacidosis (call your doctor for treatment).

Tell your doctor if you have ever had:

• kidney disease;

• heart disease;

• liver disease;

• pancreatitis;

• gallstones; or

• alcoholism.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Kazano. Be sure your caregivers know ahead of time that you are using this medicine.

Follow your doctor's instructions about using Kazano if you are pregnant or you become pregnant. Contro...