#
Klor-Con Sprinkle
  • Professionals
  • FDA PI

Klor-Con Sprinkle

Generic name:potassium chloride
Dosage form: capsule, extended release

Medically reviewed by Drugs.com. Last updated on Nov 1, 2020.

Rx only

Klor-Con Sprinkle Description

Klor-Con® Sprinkle (potassium chloride extended-release capsules, USP) Capsules 8 mEq and Klor-Con® Sprinkle (potassium chloride extended-release capsules, USP) Capsules 10 mEq are oral dosage forms of microencapsulated potassium chloride containing 600 and 750 mg, respectively, of potassium chloride USP equivalent to 8 and 10 mEq of potassium.

Dispersibility of potassium chloride (KCl) is accomplished by microencapsulation and the incorporation of a flow agent. The resultant flow characteristics of the KCl microcapsules and the controlled release of K+ ions by the microcapsular membrane are intended to avoid the possibility that excessive amounts of KCl can be localized at any point on the mucosa of the gastrointestinal tract.

Each crystal of KCl is microencapsulated by a process with an insoluble polymeric coating which functions as a semi-permeable membrane; it allows for the controlled release of potassium and chloride ions over an eight-to-ten-hour period. Fluids pass through the membrane and gradually dissolve the potassium chloride within the microcapsules. The resulting potassium chloride solution slowly diffuses outward through the membrane. Klor-Con Sprinkle (potassium chloride extended-release capsules, USP) Capsules 8 mEq and Klor-Con Sprinkle (potassium chloride extended-release capsules, USP) Capsules 10 mEq are electrolyte replenishers. The chemical name of the active ingredient is potassium chloride and the structural formula is KCl. Potassium chloride, USP occurs as a white, granular powder or as colorless crystals. It is odorless and has a saline taste. Its solutions are neutral to litmus. It is freely soluble in water and insoluble in alcohol.

The inactive ingredients are ethylcellulose, talc, gelatin and titanium dioxide. The 8 mEq blue capsules also contain FD&C Blue #1 and FD&C Red #3. The 10 mEq yellow capsules also contain D&C Yellow #10 and FD&C Red #40.

Klor-Con Sprinkle - Clinical Pharmacology

Potassium ion is the principal intracellular cation of most body tissues. Potassium ions participate in a number of essential physiological processes, including the maintenance of intracellular tonicity, the transmission of nerve impulses, the cont...