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Kloxxado
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Kloxxado

Generic name:naloxone hydrochloride
Dosage form: nasal spray
Drug class:Antidotes

Medically reviewed by Judith Stewart, BPharm. Last updated on Sep 1, 2021.

What is Kloxxado nasal spray?

  • Kloxxado nasal spray is a prescription medicine used for the treatment of an opioid emergency such as an overdose or a possible opioid overdose with signs of breathing problems and severe sleepiness or not being able to respond.
  • Kloxxado nasal spray is to be given right away and does not take the place of emergency medical care.
  • Get emergency medical help right away after giving the first dose of Kloxxado nasal spray, even if the person wakes up.
  • Kloxxado nasal spray is safe and effective in children for known or suspected opioid overdose.

You and your family members or caregivers should read this Patient Information leaflet before an opioid emergency happens. This information does not take the place of talking with your healthcare provider about your medical condition or your treatment.

Important information

Kloxxado nasal spray is used to temporarily reverse the effects of opioid medicines. The medicine in the nasal spray has no effect in people who are not taking opioid medicines. Always carry Kloxxado nasal spray with you in case of an opioid emergency.

1. Use Kloxxado nasal spray right away if you or your caregiver think signs or symptoms of an opioid emergency are present, even if you are not sure, because an opioid emergency can cause severe injury or death. Signs and symptoms of an opioid emergency may include:

    • unusual sleepiness and you are not able to awaken the person with a loud voice or by rubbing firmly on the middle of their chest (sternum)
    • breathing problems including slow or shallow breathing in someone difficult to awaken or who looks like they are not breathing
    • the black circle in the center of the colored part of the eye (pupil) is very small, sometimes called “pinpo...