Labetalol Tablets

Generic name: labetalol hydrochloride
Dosage form: tablet, film coated
Drug class:Non-cardioselective beta blockers

Medically reviewed by Drugs.com. Last updated on Mar 1, 2022.

Labetalol Tablets Description

Labetalol hydrochloride tablets, USP are an adrenergic receptor blocking agent that has both selective Alpha1-adrenergic and nonselective beta-adrenergic receptor blocking actions in a single substance. Labetalol hydrochloride is a racemate, chemically designated as 2-hydroxy-5-[1-hydroxy-2-[(1-methyl- 3-phenylpropyl)amino]ethyl]benzamide mono hydrochloride and it has the following structure:

Labetalol hydrochloride has the molecular formula C19 H24 N2 O3 •HCl and a molecular weight of 364.87. It has two asymmetric centers and therefore exists as a molecular complex of two diastereoisomeric pairs. Dilevalol, the R,R' stereoisomer, makes up 25% of racemic labetalol.

Labetalol hydrochloride, USP is a white or almost white powder. It is sparingly soluble in water and in ethanol (96%), practically insoluble in ether and in methylene chloride.

Labetalol hydrochloride tablet, USP for oral administration con...