Lamivudine and zidovudine
Generic name: lamivudine and zidovudine [ la-MIV-ue-deen-and-zye-DOE-vue-deen ]
Brand name: Combivir
Dosage form: oral tablet (150 mg-300 mg)
Drug class:Antiviral combinations
What is lamivudine and zidovudine?
Lamivudine and zidovudine are antiviral medications that prevent human immunodeficiency virus (HIV) from multiplying in your body.
Lamivudine and zidovudine is a combination medicine used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). Lamivudine and zidovudine is not a cure for HIV or AIDS.
Lamivudine and zidovudine may also be used for purposes not listed in this medication guide.
Warnings
Do not take lamivudine and zidovudine if you have ever had an allergic reaction to any medicine that contains lamivudine or zidovudine.
Zidovudine can weaken your immune system and cause signs of infection (fever, mouth sores, skin sores, flu symptoms, pale skin). Your blood will need to be tested often. Long-term use of zidovudine can cause muscle weakness, or loss of muscle tissue similar to "wasting syndrome" caused by HIV.
You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. Call your doctor or get emergency medical help if you have unusual muscle pain, trouble breathing, stomach pain, dizziness, feeling cold, or feeling very weak or tired.
If you've ever had hepatitis B, it may become active or get worse after you stop using this medicine. You may need frequent liver function tests for several months.
Before taking this medicine
You should not take this medicine if you are allergic to lamivudine. Do not take Combivir with any other medicine that contains lamivudine, zidovudine, or emtricitabine. This includes Atripla, Biktarvy, Cimduo, Combivir, Complera, Descovy, Emtriva, Epzicom, Genvoya, Odefsey, Retrovir, Stribild, Symfi, Triumeq, Trizivir, and Truvada.
Lamivudine and zidovudine can also cause severe or fatal liver problems. Tell your doctor if you have
