Lanadelumab-flyo (Subcutaneous)

Medically reviewed by Drugs.com. Last updated on May 1, 2022.

Commonly used brand name(s)

In the U.S.

• Takhzyro

Available Dosage Forms:

• Solution

Therapeutic Class: Immune Modulator

Pharmacologic Class: Lanadelumab

Uses for lanadelumab-flyo

Lanadelumab-flyo injection is used to prevent hereditary angioedema (HAE) attacks. HAE is a rare disease that causes swelling of the face, hands, feet, throat, stomach, bowels, or genitals.

Lanadelumab-flyo is available only with your doctor's prescription.

Before using lanadelumab-flyo

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lanadelumab-flyo, the following should be considered:

Allergies

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of lanadelumab-flyo injection in children younger than 12 years of age. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of lanadelumab-flyo injection in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of lanadelumab-flyo

A nurse or other trained health professional will give you lanadelumab-flyo. It is given as a shot under your skin, usually in the stomach, thighs, or upper arms. You or your caregiver may be trained to prepare and inject the medicine at home. Be sure that you understand how to use the medicine.

Lanadelumab-flyo comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

You will be shown the body areas where this shot can be given. Use a different body area each time you give yours...