Amikacin liposome (Inhalation)
Medically reviewed by Drugs.com. Last updated on Feb 10, 2022.
Amikacin liposome has been associated with an increased risk of respiratory adverse reactions, including, hypersensitivity pneumonitis, hemoptysis, bronchospasm, and exacerbation of underlying pulmonary disease that have led to hospitalizations in some cases .
Commonly used brand name(s)
In the U.S.
- Arikayce
Available Dosage Forms:
- Suspension
Therapeutic Class: Antibiotic
Chemical Class: Aminoglycoside
Uses for amikacin liposome
Amikacin liposome is used to treat adults with refractory (difficult to treat) Mycobacterium avium complex (MAC) lung disease as part of a combination antibacterial drug treatment plan (regimen). Amikacin liposome is an aminoglycoside antibiotic.
Amikacin liposome is available only with your doctor's prescription.
Before using amikacin liposome
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For amikacin liposome, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to amikacin liposome or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of amikacin liposome in the pediatric population. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of amikacin liposome in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution in the dose for patients receiving amikacin liposome.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking amikacin liposome, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using amikacin liposome with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Ethacrynic Acid
- Furosemide
- Mannitol
- Urea
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food o..