Lasmiditan
Generic name: lasmiditan
Brand name: Reyvow
Dosage form: oral tablet
Drug class:Antimigraine agents
What is lasmiditan?
Lasmiditan is a type of drug called a ditan. It is an abortive migraine medication, which means it is used to help treat a migraine attack rather than prevent a migraine headache. Lasmiditan comes as a tablet.
In 2020, lasmiditan was the first ditan to be approved by the US Food and Drug Administration (FDA).
Lasmiditan works by blocking the pain pathways in the brain. It is a serotonin (5-HT)1F receptor agonist, but its exact mechanism of action is unknown.
Unlike triptans, which are the gold-standard of treatment for migraines, lasmiditan does not constrict blood vessels in the heart and brain.
What is lasmiditan used for?
Lasmiditan is a prescription medicine used for the acute treatment of migraine attacks with or without aura in adults.
- Lasmiditan is not used as a preventive treatment of migraine.
- It is not known if lasmiditan is safe and effective in children.
- Lasmiditan is a federally controlled substance (CV) because it contains lasmiditan that can be abused. Keep lasmiditan in a safe place to protect it from theft. Never give your lasmiditan to anyone else, because it may harm them. Selling or giving away lasmiditan is against the law. Tell your healthcare provider if you have ever abused or been dependent on alcohol, prescription medicines or street drugs.
Important information
- Do not drive or operate machinery for at least 8 hours after you take lasmiditan, even if you feel well enough.
- You should not take lasmiditan if you cannot wait at least 8 hours between taking lasmiditan and driving or operating machinery.
What should I tell my doctor before taking lasmiditan?
Before you take lasmiditan, tell your healthcare provider about all of your medical conditions, including if you:
- have liver problems
- have high blood pressure
- have a low heart rate
- are allergic to lasmiditan
How should I take lasmiditan?
- Take lasmiditan exactly as your healthcare provider tells you to take it.
- Your healthcare provider may change your dose. Do not change your dose without first talking to your healthcare provider.
- Take lasmiditan tablets by mouth with or without food.
- Swallow lasmiditan tablets whole. Do not split, crush, or chew.
- Do not take more than one dose in a 24-hour period.
- If you take lasmiditan 50 mg, 100 mg, or 200 mg, and your headache goes away but comes back, you should not take a second dose within 24 hours.
- Some people who take too many lasmiditan tablets may have worse headaches (medication overuse headache). If your headaches get worse, your healthcare provider may decide to stop your treatment with lasmiditan.
- You should write down when you have headaches and when you take lasmiditan so you can talk to your healthcare provider about how lasmiditan is working for ..
