Lido-Sorb

Generic name:lidocaine hydrochloride
Dosage form: lotion

Medically reviewed by Drugs.com. Last updated on Dec 1, 2020.

Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.

Topical Anesthetic

Rx only

Lido-Sorb Description

Contains lidocaine HCl 3%. Lidocaine is chemically designated as acetamide, 2-(diethylamino)-N-(2,6- dimethylphenyl), and has the following structure:

Each gram of Lidocaine HCl 3% Lotion contains ACTIVE: Lidocaine HCl 30 mg in a lotion base of INACTIVES: aluminum sulfate, calcium acetate, cetyl alcohol, edetate disodium, glycerine, methylparaben, mineral oil, petrolatum, polysorbate 60, propylparaben, purified water, sodium hydroxide, sorbitan stearate, stearic acid and stearyl alcohol.

Lido-Sorb - Clinical Pharmacology

MECHANISM OF ACTION

Lidocaine HCl 3% Lotion releases lidocaine which stabilizes the neuronal membrane by inhibiting the ionic fluxes required for initiation and conduction of impulses, thereby effecting local anesthetic action.

PHARMACOKINETICS

Lidocaine may be absorbed following topical administration to mucous membranes, its rate and extent of absorption depending upon the specific site of application, duration of exposure, concentration and total dosage. In general, the rate of absorption of local anesthetic agents following topical application occurs most rapidly after intratracheal administration. Lidocaine is also well-absorbed from the gastrointestinal tract, but little intact drug appears in the circulation because of biotransformation in the liver.

Lidoc...