Lidocaine and epinephrine (Injection)

Medically reviewed by Drugs.com. Last updated on Apr 2, 2022.

Pharmacologic Class: Sympathomimetic

Chemical Class: Amino Amide

Uses for lidocaine and epinephrine

Lidocaine and epinephrine combination injection is used to cause numbness or loss of feeling for patients having certain medical procedures (by blocking certain nerves using the brachial plexus, intercostal, lumbar, or epidural blocking techniques).

Lidocaine and epinephrine is to be given only by or under the direct supervision of your doctor.

Before using lidocaine and epinephrine

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For lidocaine and epinephrine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to lidocaine and epinephrine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Because of lidocaine and epinephrine's toxicity, it should be used with extreme caution in children younger than 6 months of age. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment.

Geriatric

No information is available on the relationship of age to the effects of lidocaine and epinephrine combination injection in geriatric patients. However, because of lidocaine and epinephrine's toxicity, it should be used with caution. Recommended doses should not be exceeded, and the patient should be carefully monitored during treatment.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving lidocaine and epinephrine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using lidocaine and epinephrine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

• Dihydroergotamine
• Dronedarone
• Isocarboxazid
• Linezolid
• Phenelzine
• Saquinavir
• Tranylcypromine
• Vernakalant

Using lidocaine and epinephrine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

• Amifampridine