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Lidocaine and prilocaine topical
  • Treatments
  • Anesthesia

Lidocaine and prilocaine topical

Generic name: lidocaine and prilocaine topical [ LYE-doe-kane-and-PRIL-oe-kane-TOP-ik-al ]
Brand names: Emla, Emla Anesthetic Disc, Oraqix, Livixil Pak, AgonEaze, ... show all 12 brands
Dosage forms: topical cream (2.5%-2.5%); topical kit (2.5%-2.5%)
Drug class:Topical anesthetics

Medically reviewed by Drugs.com on Aug 30, 2021. Written by Cerner Multum.

What is lidocaine and prilocaine topical?

Lidocaine and prilocaine are local anesthetics (numbing medicines). They work by blocking nerve signals in your body.

Lidocaine and prilocaine topical (for the skin) is a combination medicine used to numb the skin or surfaces of the penis or vagina. lidocaine and prilocaine topical is used to prepare you for minor surgery or medical procedures on these areas.

Lidocaine and prilocaine topical may also be used for purposes not listed in this medication guide.

Warnings

An overdose of numbing medicine can cause fatal side effects if too much of the medicine is absorbed through your skin. Overdose symptoms may include uneven heartbeats, seizure (convulsions), coma, slowed breathing, or respiratory failure (breathing stops).

Use the smallest amount of this medicine needed to numb the skin. Do not use large amounts of lidocaine and prilocaine topical, or cover treated skin areas with a bandage or plastic wrap without medical advice.

Before taking this medicine

You should not use lidocaine and prilocaine topical if you are allergic to any type of numbing medicine.

Fatal overdoses have occurred when numbing medicines were used without the advice of a medical doctor (such as during a cosmetic procedure like laser hair removal). However, overdose has also occurred in women treated with a numbing medicine before having a mammography.

Be aware that many cosmetic procedures are performed without a medical doctor present.

To make sure lidocaine and prilocaine topical is safe for you, tell your doctor if you have:

  • a blood cell disorder called methemoglobinemia;

  • liver disease;

  • a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency; or

  • a family history of methemoglobinemia, or any genetic enzyme deficiency.

FDA pregnancy category B. Lidocaine and prilocain