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Lo Ovral
  • Treatments
  • Birth Control

Lo/Ovral-28

Generic name:ethinyl estradiol and norgestrelETH-in-il-ess-tra-DYE-ol-and-nor-JESS-trel ]
Brand names: Cryselle 28, Lo/Ovral-28, Low-Ogestrel, Ogestrel-28
Drug class:Contraceptives

Medically reviewed by Drugs.com. Last updated on Apr 22, 2022.

What is Lo/Ovral-28?

Lo/Ovral-28 contains a combination of ethinyl estradiol and norgestrel. Ethinyl estradiol and norgestrel are female hormones that prevent ovulation (the release of an egg from an ovary). Lo/Ovral-28 also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Lo/Ovral-28 is used as contraception to prevent pregnancy.

Lo/Ovral-28 may also be used for purposes not listed in this medication guide.

Warnings

Do not use Lo/Ovral-28 if you are pregnant or if you have recently had a baby. You should not take Lo/Ovral-28 if you have any of the following conditions: uncontrolled high blood pressure, heart disease, a blood-clotting disorder, circulation problems, diabetic problems with your eyes or kidneys, unusual vaginal bleeding, liver disease or liver cancer, severe migraine headaches, if you smoke and are over 35, or if you have ever had breast or uterine cancer, jaundice caused by Lo/Ovral-28, a heart attack, a stroke, or a blood clot.

You may need to use back up birth control, such as condoms or a spermicide, when you first start using Lo/Ovral-28 or if you miss a dose. Follow your doctor's instructions.

Missing a pill increases your risk of becoming pregnant. Carefully follow the "missed dose" instructions if you forget to take your Lo/Ovral-28.

Some drugs can make Lo/Ovral-28 less effective in preventing pregnancy, including antibiotics, hepatitis C medications, HIV/AIDS medications, seizure medications, or barbiturate sedatives. Tell your doctor about all other medications you use.

Before taking this medicine

Lo/Ovral-28 can cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking Lo/Ovral-28. You should not take Lo/Ovral-28 if you have:

  • untreated or uncontrolled high blood pressure;

  • heart disease (coronary artery disease, uncontrolled heart valve disorder, history of heart attack, stroke, or blood clot);

  • a blood-clotting disorder or circulation problems;

  • problems with your eyes, kidneys or circulation caused by diabetes;

  • a history of hormone-related cancer such as breast or uterine cancer;

  • unusual vaginal bleeding that has not been checked by a doctor;

  • liver disease or liver cancer;

  • severe migraine headaches (with aura, numbness, weakness, or vision changes),...