Lodine XL (Oral)
Generic name:etodolac (oral route) [ e-TOE-doe-lak ]
Drug class:Nonsteroidal anti-inflammatory drugs
Medically reviewed by Drugs.com. Last updated on Mar 25, 2022.
NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may be increased in patients with cardiovascular disease or risk factors for cardiovascular disease. Etodolac is contraindicated for the treatment of perioperative pain in the setting of CABG surgery. NSAIDs can also cause an increased risk of serious gastrointestinal adverse events especially in the elderly, including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal .
The Lodine XL brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
- Lodine
- Lodine XL
Available Dosage Forms:
- Tablet, Extended Release
- Tablet
- Capsule
Therapeutic Class: Analgesic
Pharmacologic Class: NSAID
Chemical Class: Acetic Acid (class)
Uses for Lodine XL
Etodolac is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (eg, osteoarthritis and rheumatoid arthritis), including inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure arthritis and will help you only as long as you continue to take it.
This medicine is available only with your doctor's prescription.
Before using Lodine XL
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Allergies
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Pediatric
Appropriate studies have not been performed on the relationship of age to the effects of etodolac capsules and tablets in the pediatric population and extended-release tablets in children younger than 6 years of age. Safety and efficacy have not been established.
Geriatric
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of etodolac in the elderly. However, elderly patients are more sensitive to the effects of etodolac than younger adults, and are more likely to have age-related kidney problems, which may require adjustment of dosage in patients receiving etodolac.
Breastfeeding
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. We..
