Lomitapide
Generic name: lomitapide [ loe-MI-ta-pide ]
Brand name: Juxtapid
Dosage form: oral capsule (10 mg; 20 mg; 5 mg)
Drug class:Miscellaneous antihyperlipidemic agents
What is lomitapide?
Lomitapide reduces blood levels of "bad" cholesterol, such as low-density lipoprotein (LDL) or non-high-density liproprotein (non-HDL), as well as a protein that carries bad cholesterol in the blood.
Lomitapide is used together with a low-fat diet and other treatments to lower total cholesterol in people with homozygous familial hypercholesterolemia (an inherited type of high cholesterol).
It is not known whether lomitapide will lower your risk of heart disease.
Lomitapide is available only under a special program. You must be registered in the program and understand the risks and benefits of lomitapide.
Lomitapide may also be used for purposes not listed in this medication guide.
Warnings
You should not use lomitapide if you have severe liver disease or a history of abnormal liver function tests.
Do not use if you are pregnant.Birth control pills may be less effective if you vomit or have diarrhea. Ask your doctor about the best way to prevent pregnancy while you are taking lomitapide.
Tell your doctor about all your current medicines and any you start or stop using. Many drugs can interact with lomitapide, and some drugs should not be used together.
Lomitapide can cause liver problems. Call your doctor at once if you have nausea, vomiting, upper stomach pain, tiredness, flu-like symptoms, dark urine, or jaundice (yellowing of the skin or eyes).
Before taking this medicine
You should not use lomitapide if you are allergic to it, or if:
you have severe liver disease;
you have abnormal liver function tests; or
you are pregnant.
Many drugs can interact and cause dangerous effects. Some drugs should not be used together with lomitapide. Your doctor may change your treatment plan if you also use:
conivaptan;
crizotinib, imatinib;
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