Loprox Gel

Generic name: ciclopirox
Dosage form: topical gel
Drug class:Topical antifungals

Medically reviewed by Drugs.com. Last updated on Jan 24, 2022.

FOR DERMATOLOGIC USE ONLY.
NOT FOR USE IN EYES.

Rx Only

Loprox Gel Description

LOPROX® Gel (ciclopirox) 0.77% contains a synthetic antifungal agent, ciclopirox. It is intended for topical dermatologic use only.

Each gram of LOPROX® Gel contains 7.70 mg of ciclopirox in a gel consisting of Purified Water USP, Isopropyl Alcohol USP, Octyldodecanol NF, Dimethicone Copolyol 190, Carbomer 980, Sodium Hydroxide NF, and Docusate Sodium USP.

LOPROX® Gel is a white, slightly fluid gel.

The chemical name for ciclopirox is 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone, with the empirical formula C12H17NO2 and a molecular weight of 207.27. The CAS Registry Number is [29342-05-0]. The chemical structure is:

Loprox Gel - Clinical Pharmacology

Mechanism of Action

Ciclopirox acts by chelation of polyvalent cations (Fe3+ or Al3+) resulting in the inhibi..