Maraviroc
Generic name: maraviroc [ ma-RAV-i-rok ]
Brand name: Selzentry
Dosage forms: oral liquid (20 mg/mL); oral tablet (150 mg; 25 mg; 300 mg; 75 mg)
Drug class:Chemokine receptor antagonist
What is maraviroc?
Maraviroc is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.
Maraviroc is used with other medications to treat CCR5-tropic HIV type 1, a virus that can cause acquired immunodeficiency syndrome (AIDS). Maraviroc is not a cure for HIV or AIDS.
Maraviroc is for use in adults and children who weigh at least 4.4 pounds (2 kilograms).
Maraviroc may also be used for purposes not listed in this medication guide.
Warnings
If you have severe kidney disease, you may not be able to take maraviroc if you use certain other medications. Tell your doctor about all other medications you use.
Stop taking maraviroc and seek medical treatment at once if you have a serious drug reaction that can harm your liver. Symptoms may include: itching or rash, vomiting, upper stomach pain, dark urine, or jaundice (yellowing of the skin or eyes).
Before taking this medicine
If you have severe or end-stage kidney disease, you may not be able to take maraviroc if you use certain medications, including some antibiotics or antifungal medications, some heart or blood pressure medicines, St. John's wort, and certain drugs to treat hepatitis or tuberculosis. Tell your doctor about all other medications you use.
Tell your doctor if you have ever had:
kidney disease (or if you are on dialysis);
liver disease, especially hepatitis B or C;
heart disease; or
Maraviroc affects your immune system and may possibly increase your risk of developing infections or cancer. Ask your doctor about this risk.
Tell your doctor if you are pregnant, and use your medications properly to control your infection. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.
Women with HIV or AIDS should not breastfeed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
Maraviroc is not approved for a premature baby, or a child who weighs less than 4.4 pounds (2 kilograms).
