Marplan
Generic name:isocarboxazid [ eye-so-kar-BOX-a-zid ]
Drug class:Monoamine oxidase inhibitors
What is Marplan?
Marplan is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain.
Marplan is used to treat symptoms of depression that may include anxiety, panic, or phobias. This medicine is usually given after other antidepressants have been tried without successful treatment of symptoms.
Marplan may also be used for purposes not listed in this medication guide.
Warnings
There are many other medicines that can cause serious medical problems or death if you take them together with Marplan. Before taking this medicine, tell your doctor about all medicines you have used within the past 5 weeks.
Do not use Marplan if you have used another MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include linezolid, methylene blue injection, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine, and others.
Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Marplan. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.
While you are taking Marplan, you must not drink alcohol or eat foods that are high in tyramine, listed in the "What should I avoid while taking this medicine?" section of this leaflet. Eating tyramine while you are taking this medicine can raise your blood pressure to dangerous levels.
What should I discuss with my doctor before taking Marplan?
You should not take Marplan if you are allergic to it, or if you have:
pheochromocytoma (tumor of the adrenal gland);
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