Melquin HP Cream
Generic name:hydroquinone
Dosage form: cream
Drug class:Topical depigmenting agents
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
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(HYDROQUINONE 4% USP SKIN BLEACHING MOISTURIZING TOPICAL CREAM)
Rx only
FOR EXTERNAL USE ONLY: NOT FOR OPHTHALMIC, NASAL OR OTIC USE.
Melquin HP Cream Description
Each gram of MELQUIN® HP 4% CREAM Contains: ACTIVE: 40mg Hydroquinone USP in a cream base of INACTIVES: Cetostearyl Alcohol, Glycerine, Mineral Oil, Propylene Glycol, Purified Water, Sodium Lauryl Sulfate, Sodium Metabisulfite, Sorbic Acid and White Petrolatum.
Hydroquinone is 1, 4-Benzenediol, with a chemical formula of C6H6O2 and a molecular weight of 110.11.
The structural formula is:

C6H6O2
Melquin HP Cream - Clinical Pharmacology
Topical application of hydroquinone produces a reversible depigmentation of the skin by the inhibition of the enzymatic oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (DOPA) [Denton, C., et al., 1952 (1)] and suppression of other melanocyte metabolic processes [Jimbow, K., et al., 1974 (2)]. Exposure to sunlight or ultraviolet light will cause repigmentation of the bleached areas [Parrish, J.A. et al., 1978 (3)].
Indications and Usage for Melquin HP Cream
MELQUIN® HP 4% CREAM is indicated for the gradual bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undesired areas of melanin hyperpigmentation.
Contraindications
MELQUIN® HP 4% CREAM is contraindicated in persons who have show...