Melquin-3 Solution
Generic name:hydroquinone
Dosage form: topical liquid
Drug class:Topical depigmenting agents
Medically reviewed by Drugs.com. Last updated on Oct 22, 2021.
Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. For further information about unapproved drugs, click here.
On This Page
(HYDROQUINONE 3% SKIN BLEACHING TOPICAL SOLUTION)
Rx only
The Melquin-3 brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Melquin-3 Solution Description
Each mL of MELQUIN-3® TOPICAL SOLUTION contains ACTIVE: Hydroquinone 3.0% (30 mg) INACTIVES: SD Alcohol 40B (45% by volume), Purified Water, Isopropyl Alcohol(4% by volume), Propylene Glycol, Laureth-4, Hydroxyethyl Cellulose and Ascorbic Acid.
Hydroquinone is 1, 4-Benzenediol, with a chemical formula of C6H6O2 and a molecular weight of 110.11. The structural formula is:

C6H6O2
Melquin-3 Solution - Clinical Pharmacology
Topical application of hydroquinones produce a reversible depigmentation of the skin by the inhibition of the enzymatic oxidation of tyrosine to 3, 4-dihydroxyphenylalanine (DOPA) [Denton, C., et al , 1952 (1)] and suppression of other melanocyte metabolic processes [Jimbow, K., et al, 1974 (2)]. Exposure to sunlight or ultraviolet light will cause repigmentation of the bleached areas [Parrish, J., et al, 1978 (3)].
Indications and Usage for Melquin-3 Solution
MELQUIN-3® TOPICAL SOLUTION is indicated for the temporary bleaching of hyperpigmented skin conditions such as chloasma, melasma, freckles, senile lentigines and other undes...