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Mepivacaine and Levonordefrin
  • Professionals
  • FDA PI

Mepivacaine and Levonordefrin

Generic name: mepivacaine hydrochloride and levonordefrin
Dosage form: injection, solution

Rx Only

THESE SOLUTIONS ARE INTENDED FOR DENTAL USE ONLY.

Mepivacaine and Levonordefrin Description

Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic, is 1-methyl-2', 6' - pipecoloxylidide monohydrochloride with the following structural formula:

It is a white, crystalline, odorless powder soluble in water, but very resistant to both acid and alkaline hydrolysis.

Levonordefrin, a sympathomimetic amine used as a vasoconstrictor in local anesthetic solution, is (-)-α-(1-Aminoethyl)-3, 4-dihydroxybenzyl alcohol with the following structural formula:

It is a white or buff-colored crystalline solid, freely soluble in aqueous solutions of mineral acids, but practically insoluble in water;

DENTAL CARTRIDGES MAY NOT BE AUTOCLAVED.

Mepivacaine hydrochloride injection 3% (30 mg/mL) and Mepivacaine hydrochloride 2% (20 mg/mL) with levonordefrin 1:20,000 injection are sterile solutions for injection.

COMPOSITION:CARTRIDGE
Each mL contains:2%3%
Mepivacaine Hydrochloride20 mg30 mg
Levonordefrin0.05 mg-
Sodium Chloride4 mg6 mg
Potassium metabisulfite1.2 mg-
Edetate disodium0.2...