Mepivacaine and Levonordefrin
Generic name: mepivacaine hydrochloride and levonordefrin
Dosage form: injection, solution
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THESE SOLUTIONS ARE INTENDED FOR DENTAL USE ONLY.
Mepivacaine and Levonordefrin Description
Mepivacaine Hydrochloride, a tertiary amine used as a local anesthetic, is 1-methyl-2', 6' - pipecoloxylidide monohydrochloride with the following structural formula:
It is a white, crystalline, odorless powder soluble in water, but very resistant to both acid and alkaline hydrolysis.
Levonordefrin, a sympathomimetic amine used as a vasoconstrictor in local anesthetic solution, is (-)-α-(1-Aminoethyl)-3, 4-dihydroxybenzyl alcohol with the following structural formula:
It is a white or buff-colored crystalline solid, freely soluble in aqueous solutions of mineral acids, but practically insoluble in water;
DENTAL CARTRIDGES MAY NOT BE AUTOCLAVED.
Mepivacaine hydrochloride injection 3% (30 mg/mL) and Mepivacaine hydrochloride 2% (20 mg/mL) with levonordefrin 1:20,000 injection are sterile solutions for injection.
COMPOSITION: | CARTRIDGE | |
---|---|---|
Each mL contains: | 2% | 3% |
Mepivacaine Hydrochloride | 20 mg | 30 mg |
Levonordefrin | 0.05 mg | - |
Sodium Chloride | 4 mg | 6 mg |
Potassium metabisulfite | 1.2 mg | - |
Edetate disodium | 0.2... |