Generic name:vestronidase alfa [ ves-TRON-i-dase-AL-fa ]
Drug class:Lysosomal enzymes
What is Mepsevii?
Mepsevii contains an enzyme that occurs naturally in the body in healthy people. Some people lack this enzyme because of a genetic disorder. This medicine helps replace this missing enzyme in such people.
Mepsevii is used to treat some of the symptoms of a genetic condition called mucopolysaccharidosis VII (MYOO-koe-pol-ee-SAK-a-rye-DOE-sis Seven) or MPS VII, also called Sly syndrome.
MPS VII is a metabolic disorder in which the body lacks the enzyme needed to break down certain natural substances. These substances can build up in the body, causing enlarged organs, abnormal bone structure, changes in facial features, breathing problems, heart problems, vision or hearing loss, and changes in mental or physical abilities.
Mepsevii may improve walking ability in people with this condition. However, this medication is not a cure for MPS VII.
Mepsevii may also be used for purposes not listed in this medication guide.
Warnings
An allergic reaction may occur during or shortly after infusion of Mepsevii. Tell your caregivers or get emergency medical help right away if you have any signs of a severe allergic reaction, such as sweating, trouble breathing, pale skin, blue lips or fingernails, and feeling like you might pass out.
Before taking this medicine
Tell your doctor if you have ever had:
a lung disease or breathing problems.
Tell your doctor if you are pregnant or breastfeeding.
