Amphadase
Generic name:hyaluronidase (injection) [ HYE-al-ure-ON-i-dase ]
Brand names: Amphadase, Hylenex, Vitrase
Drug class:Miscellaneous uncategorized agents
Medically reviewed by Drugs.com. Last updated on Sep 22, 2021.
What is Amphadase?
Amphadase is a genetically designed protein.
Amphadase is used together with fluids injected into the body to treat dehydration. Hyaluronidase can also be used as an aid in helping your body absorb other injected medications.
Amphadase is also used to help contrast dyes in your body show more clearly on certain types of x-rays or scans.
Warnings
Serious drug interactions can occur when certain medicines are used together with Amphadase. Tell your doctor about all your current medicines.
Before receiving Amphadase, tell your doctor if you are using any of the following drugs: furosemide (Lasix); phenytoin (Dilantin); a sedative or anxiety medication (such as Valium, Xanax, Tranxene); aspirin or salicylates; cortisone or ACTH (Corticotropin); estrogens; or an antihistamine (such as a cold or allergy medicine).
Your doctor may perform a skin test before using Amphadase to see if you are allergic to hyaluronidase.
Before receiving this medicine
You should not be treated with Amphadase if you are allergic to hyaluronidase.
Your doctor may perform a skin test to see if you are allergic to hyaluronidase before you receive the medication.
Some medicines can cause unwanted or dangerous effects when used with Amphadase. Your doctor may need to change your treatment plan if you use any of the following drugs:
furosemide (Lasix);
phenytoin (Dilantin);
a sedative or anxiety medication (such as diazepam, lorazepam, alprazolam, Valium, Xanax, Ativan, Tranxene, and others);
aspirin or salicylates;
cortisone or ACTH (Corticotropin);
estrogens; or
an antihistamine (such as a cold or allergy medicine).
Tell your doctor if you are pregnant or plan to become pregnant.
It may not be safe to breast-feed while using Amphadase. Ask your doctor about any risk.
How is Amphadase given?
Amphadase is injected under the skin, into a muscle, or into other tissues of the body.
A healthcare provider will give you this injection.
Amphadase should not be injected into a vein (as an intravenous injection).
What happens if I miss a dose?
Because you will receive Amphadase in a clinical setting, you are not likely to miss a dose.
